Ano in Vitro-in Vivo Models
نویسندگان
چکیده
Tue recognised validity of iontophoresis in promoting the dennal or transdennal transport of biologically active compounds, mainly ionized species, to gain a systemic effect, is related to an accurately and controlled choice of materials and devices, as well as of the operative conditions used for its realization. Extensive work has been done with in vitro experimental models to better define the different factors which can influence the effectiveness and reliability of iontophoresis. In this paper, we took into considerations such parameters, illustrating also the in vitro and in vivo models and devices, developed during last years.
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